Related Experiment Video
Updated: Nov 17, 2025

Highlighting and Reducing the Impact of Negative Aging Stereotypes During Older Adults' Cognitive Testing
Published on: January 24, 2020
Age-related cognitive bias in in-hospital cardiac arrest
Mathias J Holmberg1, Asger Granfeldt2, Ari Moskowitz3
1Research Center for Emergency Medicine, Department of Clinical Medicine, Aarhus University and Aarhus University Hospital, Aarhus, Denmark; Center for Resuscitation Science, Department of Emergency Medicine, Beth Israel Deaconess Medical Center, Boston, MA, USA; Department of Cardiology, Viborg Regional Hospital, Viborg, Denmark.
Insights
This study found no evidence that left-digit bias in patient age affects outcomes for in-hospital cardiac arrest. Survival rates remained consistent across age thresholds, indicating cognitive bias did not impact clinical decisions in this setting.
Area of Science:
- Medical Error and Patient Safety
- Cardiology and Critical Care Medicine
- Cognitive Psychology in Healthcare
Background:
- Cognitive bias can influence clinical decision-making and potentially lead to medical errors.
- Left-digit bias, a specific cognitive bias, involves overemphasizing the leftmost digit of a number, potentially affecting clinical judgment.
- Understanding the impact of cognitive bias on patient outcomes is crucial for improving healthcare quality.
Purpose of the Study:
- To investigate the influence of left-digit bias, specifically related to patient age, on outcomes following in-hospital cardiac arrest.
- To determine if age thresholds (e.g., 80 years) show a sudden change in survival rates, suggesting cognitive bias in clinical assessment.
- To analyze the association between cognitive bias and patient survival, return of spontaneous circulation, neurological outcome, and resuscitation duration.
Main Methods:
- Utilized the Get With The Guidelines® - Resuscitation registry, including adult patients with in-hospital cardiac arrest from 2011 to 2019.
- Employed a regression discontinuity design to assess survival changes around specific age thresholds (60, 70, 80, and 90 years).
- Primary outcome was survival to hospital discharge; secondary outcomes included return of spontaneous circulation, neurological outcome, and resuscitation duration.
Main Results:
- A total of 26,784 patients were analyzed, with an overall survival rate of 22%.
- No significant discontinuity in survival rates was observed below and above the age of 80 years (risk difference, 0.47%; 95% CI, -1.61% to 2.56%).
- Similar findings were consistent across secondary outcomes and other age thresholds, confirmed by sensitivity analyses.
Conclusions:
- The study found no evidence that cognitive bias related to patient age influences outcomes in patients experiencing in-hospital cardiac arrest.
- Clinical decision-making regarding cardiac arrest management did not appear to be significantly affected by left-digit bias in this large patient cohort.
- These findings suggest that age-related cognitive biases may not be a major confounder for patient outcomes in this specific critical care setting.
Aims:
Cognitive bias has been recognized as a potential source of medical error as it may affect clinical decision making. In this study, we explored how cognitive bias, specifically left-digit bias, may affect patient outcomes in in-hospital cardiac arrest.
Methods:
Using the Get With The Guidelines® - Resuscitation registry, we included adult patients with an in-hospital cardiac arrest from 2011 to 2019. The primary outcome was survival to hospital discharge. Secondary outcomes included return of spontaneous circulation, favorable neurological outcome, and duration of resuscitation. Using a regression discontinuity design, we explored whether there was a sudden change in survival at the age threshold of 80 years which would indicate left-digit bias. Additional analyses were performed at age thresholds of 60, 70, and 90 years.
Results:
A total of 26,784 patients were included for the primary analysis. The overall survival was 22% in this cohort. There was no discontinuity of survival below and above the age of 80 years (risk difference, 0.47%; 95%CI, -1.61% to 2.56%). Similar results were estimated for the secondary outcomes and for the age thresholds of 60, 70, and 90 years. The results were consistent in sensitivity analyses.
Conclusions:
There was no indication that cognitive bias based on age affected outcomes in in-hospital cardiac arrest in these data.
Related Concept Videos
The Availability Heuristic
Motivational Bias
Eyewitness Memory
One such error is memory distortion, which occurs because human memory does not function...
Cardiopulmonary Resuscitation IV: Pharmacological Management
Pharmacodynamics in Geriatric Patients: Effects of Age

