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Controlled-Current Coulometry: Overview01:27

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Controlled current coulometry, also known as amperostatic coulometry, is a technique used in electrochemical analysis to measure the quantity of a substance through the controlled passage of current. It involves the application of a constant current to an electrochemical cell containing the analyte of interest. As the current flows through the cell, the analyte undergoes a redox reaction at the electrode surface, resulting in a charge transfer. By monitoring the time required for a certain...
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Color in Coordination Complexes
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Coulometric titrations are a form of titrimetric analysis where the reagent is generated electrically, and its amount is evaluated based on current and generating time. The electron serves as the standard reagent. The procedure is similar to conventional titrations, such as endpoint detection.
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Related Experiment Video

Updated: Nov 17, 2025

A Dual-Functional Electroactive Filter Towards Simultaneously SbIII Oxidation and Sequestration
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Controllable and reversible sensing cyanide ion using dual-functional Cu(II)-based ensemble.

Jun Wang1, Jinjun He1, Jinsheng Zhang1

  • 1Key Lab of Functional Materials Chemistry of Guizhou Province, School of Chemistry and Materials Science, Guizhou Normal University, Guiyang 550025, China.

Spectrochimica Acta. Part A, Molecular and Biomolecular Spectroscopy
|February 14, 2021
PubMed
Summary

A novel dual-functional copper ensemble (2S·Cu2+) enables selective detection of cyanide (CN-) over phosphate and biothiols. This sensor demonstrates reversibility and reusability for environmental monitoring applications.

Keywords:
BiothiolsCyanideDeprotonationEnsembleIndicator displacement approach

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Area of Science:

  • Analytical Chemistry
  • Materials Science
  • Environmental Science

Background:

  • Selective detection of cyanide ions (CN-) is crucial for environmental and biological safety.
  • Existing sensing methods often face challenges with selectivity and interference from other species like phosphate (H2PO4-) and biothiols.

Purpose of the Study:

  • To design and characterize a dual-functional copper ensemble (2S·Cu2+) for selective and sensitive detection of CN-.
  • To investigate the sensing mechanism and evaluate the sensor's performance in discriminating CN- from interfering species.
  • To explore the reversibility, reusability, and sequential sensing capabilities of the developed system.

Main Methods:

  • Design and characterization of a dual-functional copper ensemble (2S·Cu2+).
  • Utilizing disaggregation of the ensemble and deprotonation of the sensor for CN- detection.
  • Employing 1H NMR, HRMS, and UV-Vis spectroscopy to elucidate the sensing mechanism.
  • Investigating reversibility and reusability through alternating addition of analytes and ions.
  • Developing test paper strips for sequential sensing applications.

Main Results:

  • The 2S·Cu2+ ensemble successfully achieved successional and discriminating sensing of CN-.
  • The sensing mechanism involves ensemble disaggregation and imidazole NH deprotonation, confirmed by spectroscopic data and energy gap analysis.
  • The sensor exhibited excellent reversibility and reusability upon alternating addition of CN-/H+ and CN-/Cu2+.
  • Sequential sensing of biothiols and CN- was successfully realized using spectroscopic methods and test paper strips.

Conclusions:

  • The developed Cu2+-based ensemble provides a feasible strategy for highly selective and sensitive discrimination of CN- over H2PO4- and biothiols.
  • The dual-functional nature and reversible operation of the sensor offer potential for practical applications in environmental monitoring.
  • This work presents a promising approach for developing advanced chemical sensors with enhanced performance.