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[Reflux disease and cancer].

M Rossetti1

  • 1Chirurgischen Klinik, Kantonsspitals Liestal, Universität Basel.

Zentralblatt Fur Chirurgie
|January 1, 1988
PubMed
Summary

Gastroesophageal reflux disease carries a 10% malignant potential. While early surgical intervention can reduce risks, preventive removal of endobrachyesophagus is not recommended due to high biological costs.

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Area of Science:

  • Gastroenterology
  • Surgical Oncology
  • Oesophageal Diseases

Context:

  • Endobrachyesophagus and reflux disease present a significant malignant potential.
  • Neoplasias are predominantly found in the distal and central esophagus.
  • Dysphagia develops in only 50% of cases with prolonged reflux.

Purpose:

  • To evaluate the malignant potential of endobrachyesophagus and reflux disease.
  • To analyze surgical outcomes for operable esophageal malignancies.
  • To assess the efficacy of early surgical treatment for aggressive reflux.

Summary:

  • Malignant transformation in endobrachyesophagus occurs in approximately 10% of cases.
  • A specific abdomino-thoracic surgical approach involving gastric pull-up is detailed for operable tumors.
  • Early surgical management of reflux disease may mitigate but not eliminate malignant degeneration risk.

Impact:

  • Highlights the 10% malignant potential of endobrachyesophagus, guiding clinical vigilance.
  • Provides insights into surgical management and outcomes for esophageal cancer.
  • Suggests that preventive esophagectomy for endobrachyesophagus is not currently justified due to high morbidity.

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