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Related Experiment Videos

Naproxen nephrotoxicity in a 2-year-old child.

P E Ray1, D Rigolizzo, D R Wara

  • 1Department of Pediatrics, University of California, San Francisco.

American Journal of Diseases of Children (1960)
|May 1, 1988
PubMed
Summary

Nonsteroidal anti-inflammatory drugs (NSAIDs) can cause acute kidney injury and interstitial nephritis in children, though rare. This case highlights a 2-year-old boy who developed these conditions after naproxen sodium treatment.

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Area of Science:

  • Pediatric Nephrology
  • Clinical Pharmacology
  • Rheumatology

Background:

  • Nonsteroidal anti-inflammatory drugs (NSAIDs) are frequently used for pain and inflammation.
  • NSAID-induced nephrotoxicity, including acute renal failure and interstitial nephritis, is well-documented in adults.
  • This complication is considered rare in pediatric populations.