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Related Experiment Videos

Necrotizing enterocolitis in full-term infants. A case-control study.

T E Wiswell1, C F Robertson, T A Jones

  • 1Neonatology Services, Brooke Army Medical Center, San Antonio, Tex.

American Journal of Diseases of Children (1960)
|May 1, 1988
PubMed
Summary
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Necrotizing enterocolitis (NEC) in full-term infants is linked to specific risk factors like perinatal asphyxia and umbilical catheters. Early identification and management are crucial for these vulnerable newborns.

Area of Science:

  • Neonatal Medicine
  • Pediatric Surgery

Background:

  • Necrotizing enterocolitis (NEC) is a severe gastrointestinal condition primarily affecting preterm infants.
  • Understanding NEC in full-term infants is crucial due to potential unique risk factors and outcomes.

Purpose of the Study:

  • To investigate risk factors and clinical features of NEC in full-term infants.
  • To compare NEC characteristics between full-term and preterm infants.

Main Methods:

  • A case-control study involving 43 full-term infants diagnosed with NEC.
  • Two control groups of term infants were utilized: healthy controls and sick controls without NEC.

Main Results:

  • Full-term infants with NEC represented 12.7% of all NEC cases.

Related Experiment Videos

  • Identified risk factors include perinatal asphyxia, umbilical catheters, respiratory distress, polycythemia, and maternal preeclampsia.
  • Sick infants, especially those small for gestational age or requiring exchange transfusions, are at higher risk.

    • Conclusions:

    • NEC in full-term infants is associated with specific perinatal complications.
    • Prompt recognition and aggressive management are recommended for term infants exhibiting suggestive symptoms.