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Insulin is released by beta cells of the pancreas when blood glucose levels are high. It facilitates glucose absorption and utilization in insulin-dependent cells with insulin receptors on their plasma membranes. Insulin promotes glucose uptake by increasing the number of glucose transport proteins in the cell membrane, allowing glucose to enter the cell. As a result, glucose utilization and ATP production are enhanced.
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Carbohydrates consumed through foods are converted into glucose, a crucial energy source for the body. In the prandial state, high blood glucose levels stimulate the secretion of insulin from the pancreas. Insulin inhibits hepatic glucose production and stimulates glucose uptake and metabolism by muscle and adipose tissue. The excess glucose is converted into glycogen and stored in the liver and muscles.
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Type 2 diabetes, characterized by insulin resistance, arises when the insulin receptors on cells lose responsiveness to insulin, diminishing the cell's capacity to take up glucose, resulting in elevated blood glucose levels. To receive a diagnosis of Type 2 diabetes, a series of blood glucose tests are necessary to assess whether the blood glucose falls within normal parameters. If the result is out of the normal range, a patient may be diagnosed as prediabetic or diabetic, depending on the...
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Diabetes mellitus is a chronic metabolic disorder characterized by high blood glucose levels due to inadequate insulin production, insulin resistance, or both. The condition affects millions worldwide and can significantly impact their health and quality of life.
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Glucose transporters facilitate the transport of glucose across the cell membrane. In addition to glucose, some glucose transporters can also aid the movement of other hexoses such as fructose, mannose, and galactose.
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The OhioT1DM Dataset for Blood Glucose Level Prediction: Update 2020.

Cindy Marling1, Razvan Bunescu1

  • 1Ohio University, USA.

CEUR Workshop Proceedings
|February 15, 2021
PubMed
Summary

The OhioT1DM Dataset offers valuable data for type 1 diabetes research, including continuous glucose monitoring and physiological sensor information. This expanded dataset aids blood glucose level prediction research.

Area of Science:

  • Biomedical Informatics
  • Endocrinology
  • Data Science

Background:

  • Type 1 diabetes management requires accurate blood glucose level prediction.
  • Existing datasets may lack comprehensive, integrated data for advanced research.
  • The OhioT1DM Dataset was created to address this need.

Purpose of the Study:

  • To document and release the expanded OhioT1DM Dataset for type 1 diabetes research.
  • To facilitate and promote research in blood glucose level prediction.
  • To provide researchers with integrated physiological and self-reported data.

Main Methods:

  • Collected eight weeks of data for 12 individuals with type 1 diabetes.
  • Included continuous glucose monitoring, insulin, physiological sensor, and life-event data.

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  • Developed an associated graphical software tool for data visualization.
  • Main Results:

    • The OhioT1DM Dataset now contains data for 12 individuals, doubled from its initial release.
    • The dataset integrates multiple data types for a holistic view of diabetes management.
    • A detailed paper describes the dataset's content, format, and acquisition process.

    Conclusions:

    • The OhioT1DM Dataset is a valuable resource for advancing blood glucose prediction models.
    • The updated dataset supports the second Blood Glucose Level Prediction Challenge.
    • This work supersedes previous documentation of the dataset.