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A Systematic Review Examining the Potential Adverse Effects of Microneedling
Asha Gowda1,2,3, Brayden Healey1,2,3, Harib Ezaldein1,2,3
1Drs. Gowda and Ezaldein are with the Department of Dermatology, University Hospitals Cleveland Medical Center in Cleveland, Ohio.
The Journal of Clinical and Aesthetic Dermatology
|February 15, 2021
Summary
Microneedling is a safe dermatological procedure for various skin conditions. This review found minimal adverse effects, primarily temporary skin irritation, erythema, and pain, emphasizing informed patient and clinician awareness.
Area of Science:
- Dermatology
- Aesthetic Medicine
- Minimally Invasive Procedures
Background:
- Microneedling is a popular therapeutic technique for diverse dermatological issues like acne, alopecia, and pigmentary disorders.
- It is increasingly utilized in clinical and at-home settings for skin rejuvenation and scar treatment.
- Understanding its adverse effects is crucial due to its widespread application.
Purpose of the Study:
- To systematically review the literature on microneedling procedures.
- To identify and describe potential complications associated with microneedling.
- To assess the safety profile of microneedling across different devices and conditions.
Main Methods:
- A systematic literature review was conducted using PubMed.
- Studies involving various microneedling devices (roller, stamp, pen-type, fractional RF) were identified.
- Included publications were analyzed for reported adverse effects and complications.
Main Results:
- A total of 51 articles comprising 1,029 patients were reviewed.
- Microneedling was found to be a relatively safe procedure across all device types.
- Minimal adverse effects were observed, including expected erythema, pain, edema, and temporary skin irritation.
Conclusions:
- Microneedling is an attractive treatment option for numerous dermatological conditions.
- Clinicians and patients should be aware of potential side effects.
- Informed awareness can help reduce or avoid preventable complications associated with microneedling.

