Etiological Association Between Psoriasis and Thyroid Diseases

Area of Science:

• Autoimmune diseases
• Dermatology
• Endocrinology

Background:

• Psoriasis is a chronic autoimmune condition affecting skin and nails.
• It frequently co-occurs with other autoimmune disorders, including thyroid diseases such as Hashimoto's thyroiditis and Grave's disease.
• These thyroid conditions impact major organs and bodily functions.

Purpose of the Study:

• To conduct an in-depth analysis of the association between psoriasis and thyroid diseases.
• To explore common etiological factors and the role of autoimmunity in this relationship.
• To review existing literature on the connection between psoriasis and thyroid autoimmunity.

Main Methods:

• A comprehensive literature search was performed on PubMed.
• Both regular and Medical Subject Headings (MeSH) keywords were utilized.
• Forty-five relevant articles were selected for analysis.

Main Results:

• A positive association between psoriasis and thyroid diseases was observed in most reviewed articles.
• This association appears more prevalent in patients with obesity and late-onset psoriasis.
• Some studies indicated no significant connection, highlighting the need for more research.

Conclusions:

• While a link between psoriasis and thyroid diseases is suggested, concrete explanations are limited due to insufficient research.
• Additional studies are crucial to elucidate the underlying mechanisms.
• Clinicians and researchers should consider integrated care, including thyroid evaluation for psoriasis patients, potentially leading to more efficient treatment strategies.