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Sodium Fluorescein for Spinal Intradural Tumors
Semih Kivanc Olguner1, Ali Arslan1, Vedat Açık1
1Department of Neurosurgery, Adana City Training and Research Hospital, Adana, Turkey.
Frontiers in Oncology
|February 15, 2021
Summary
Sodium (Na)-fluorescein dye aids spinal tumor surgery. This dye helps surgeons differentiate tumor from healthy tissue in most intradural extramedullary and intramedullary tumor resections, improving surgical outcomes.
Area of Science:
- Neurosurgery
- Surgical Oncology
- Medical Technology
Background:
- Surgical treatment of spinal intradural tumors benefits from technological advancements.
- Sodium (Na)-fluorescein guidance is established for cranial surgeries but less studied for spinal tumors.
Purpose of the Study:
- To evaluate the utility of Na-fluorescein under a yellow filter microscope for spinal intradural tumor surgery.
- To assess its effectiveness in distinguishing tumor tissue from healthy spinal cord tissue.
Main Methods:
- Retrospective review of 49 adult patients undergoing spinal intradural tumor surgery with Na-fluorescein guidance.
- Analysis of demographic data, tumor type (intramedullary vs. extramedullary), Na-fluorescein staining patterns, and surgical resection extent.
- Statistical analysis of the dye's usefulness in tumor differentiation.
Main Results:
- Na-fluorescein staining was helpful in 95.9% of cases.
- It was effective in 100% of extramedullary tumors and 86.7% of intramedullary tumors.
- Staining patterns varied, being homogeneous in most extramedullary and some intramedullary tumors.
Conclusions:
- Na-fluorescein under a yellow filter microscope is a valuable tool for spinal intradural tumor surgery.
- It effectively assists surgeons in differentiating tumor from healthy tissue, enhancing resection.
- The dye provides significant aid in both intramedullary and extramedullary spinal tumor removal.
