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Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report
Joana Correia Lopes1, Andreia Sofia Basílio2, Mário Amaro1
1Internal Medicine Department, Hospital Garcia de Orta EPE, Almada, Portugal.
Insights
Community-acquired pyogenic ventriculitis is rare in adults. This case highlights a successful treatment of a 71-year-old man with E. coli-induced pyogenic ventriculitis, emphasizing MRI for diagnosis and prolonged antibiotics for recovery.
Area of Science:
- Neurology
- Infectious Diseases
- Radiology
Background:
- Pyogenic ventriculitis, an infection of cerebral ventricles, is typically linked to neurosurgery or head trauma.
- Community-acquired pyogenic ventriculitis in adults is exceptionally rare, with fewer than 10 cases reported.
- The patient presented with urosepsis and a fluctuating level of consciousness.
Purpose of the Study:
- To report a rare case of community-acquired pyogenic ventriculitis in an adult.
- To illustrate the diagnostic utility of MRI in such cases.
- To highlight effective treatment strategies for pyogenic ventriculitis.
Main Methods:
- A 71-year-old male patient with type 2 diabetes mellitus and urosepsis was evaluated.
- Magnetic Resonance Imaging (MRI) was performed due to altered consciousness.
- Treatment involved a 6-week course of ceftriaxone.
Main Results:
- MRI diagnosed pyogenic ventriculitis.
- The patient received prolonged antibiotic treatment with ceftriaxone.
- Recovery was achieved without any neurological deficits.
Conclusions:
- Community-acquired pyogenic ventriculitis is a rare clinical entity with atypical presentations, often lacking meningism.
- Magnetic Resonance Imaging (MRI) is crucial for accurate diagnosis.
- Extended antibiotic therapy is recommended for successful treatment outcomes.
Abstract:
Pyogenic ventriculitis is an infection of the cerebral ventricles usually associated with neurosurgery or head trauma. There are less than 10 reported cases of community-acquired pyogenic ventriculitis in adults. We present the case of a 71-year-old man with a medical history of type 2 diabetes mellitus, hospitalized due to urosepsis caused by E. coli. Because he had a fluctuant level of consciousness, he underwent magnetic resonance imaging that diagnosed pyogenic ventriculitis. He was treated with ceftriaxone 2 g 12/12h for a total of 6 weeks and recovered without neurological deficits. Pyogenic ventriculitis is a clinical challenge due to its rarity, atypical presentation and variety of aetiological microorganisms.
Learning Points:
Pyogenic ventriculitis is an infection of the cerebral ventricles usually associated with neurosurgery or head trauma; community-acquired primary pyogenic ventriculitis is very rare.Presentation is atypical (no meningism), multiple microorganisms can be involved, and it should be treated with prolonged antibiotic regimens.MRI is the most useful exam for diagnosis.
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