Pyogenic Ventriculitis Associated with Urosepsis: A Rare Case Report

Joana Correia Lopes1, Andreia Sofia Basílio2, Mário Amaro1

  • 1Internal Medicine Department, Hospital Garcia de Orta EPE, Almada, Portugal.

Insights

Community-acquired pyogenic ventriculitis is rare in adults. This case highlights a successful treatment of a 71-year-old man with E. coli-induced pyogenic ventriculitis, emphasizing MRI for diagnosis and prolonged antibiotics for recovery.

Area of Science:

  • Neurology
  • Infectious Diseases
  • Radiology

Background:

  • Pyogenic ventriculitis, an infection of cerebral ventricles, is typically linked to neurosurgery or head trauma.
  • Community-acquired pyogenic ventriculitis in adults is exceptionally rare, with fewer than 10 cases reported.
  • The patient presented with urosepsis and a fluctuating level of consciousness.

Purpose of the Study:

  • To report a rare case of community-acquired pyogenic ventriculitis in an adult.
  • To illustrate the diagnostic utility of MRI in such cases.
  • To highlight effective treatment strategies for pyogenic ventriculitis.

Main Methods:

  • A 71-year-old male patient with type 2 diabetes mellitus and urosepsis was evaluated.
  • Magnetic Resonance Imaging (MRI) was performed due to altered consciousness.
  • Treatment involved a 6-week course of ceftriaxone.

Main Results:

  • MRI diagnosed pyogenic ventriculitis.
  • The patient received prolonged antibiotic treatment with ceftriaxone.
  • Recovery was achieved without any neurological deficits.

Conclusions:

  • Community-acquired pyogenic ventriculitis is a rare clinical entity with atypical presentations, often lacking meningism.
  • Magnetic Resonance Imaging (MRI) is crucial for accurate diagnosis.
  • Extended antibiotic therapy is recommended for successful treatment outcomes.

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