Related Experiment Video For Cholangiocarcinoma
Updated: Nov 17, 2025

Laparoscopic Choledochal Cyst Excision and Roux-en-Y Choledochojejunostomy in Adults
Published on: February 28, 2025
Missed Diagnosis of Cholangiocarcinoma Presenting with Atypical Symptoms
Ren Kawamura1, Yukinori Harada1, Taro Shimizu1
1Department of Diagnostic and Generalist Medicine, Dokkyo Medical University Hospital, Mibu, Tochigi, Japan.
Abstract:
We report a case of delayed diagnosis of cholangiocarcinoma. A 62-year-old man developed acute abdominal pain in multiple sites. As the distribution pattern of the abdominal pain was not correctly interpreted based on the mechanisms of visceral and referred pain, the patient was not investigated with the best diagnostic test at first presentation. Moreover, miscommunication between physicians in a clinic and separate hospital delayed diagnosis. For prompt diagnosis, physicians should be practice careful reasoning and focus on good communication with physicians outside their hospital.
Learning Points:
Abdominal pain without jaundice can be an initial symptom in patients with cholangiocarcinoma.Cholangiocarcinoma in the lower common bile duct can present as lower abdominal pain referred through the 7th-11th thoracic nerves.Physicians can determine the origin of abdominal pain through correct interpretation of the distribution pattern of abdominal pain based on knowledge of pathophysiology.
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