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Hypertension, BMI, and cardiovascular and cerebrovascular diseases

Wenjing Qiao1, Xinyi Zhang2, Bo Kan3

  • 1Department of Epidemiology and Biostatistics, School of Public Health, Jilin University, 232-1163 Xinmin Street, Changchun, 130021, Jilin, China.

Open Medicine (Warsaw, Poland)
|February 15, 2021
PubMed

Insights

Higher body mass index (BMI) increases the risk of cardiovascular and cerebrovascular diseases (CCDs). This association is significantly stronger in individuals with hypertension, highlighting the importance of weight management for this population.

Area of Science:

  • Cardiology
  • Public Health
  • Epidemiology

Background:

  • Hypertension is linked to body mass index (BMI) and cardiovascular and cerebrovascular diseases (CCDs).
  • The interplay between BMI, hypertension, and CCDs requires further investigation.

Purpose of the Study:

  • To examine the association between BMI and CCDs.
  • To determine if hypertension modifies the relationship between BMI and CCDs.

Main Methods:

  • A population-based sample of 3,942 participants from Liaoning, China, was analyzed.
  • Hypertension was defined by medication use or blood pressure thresholds (≥130/80 mmHg).
  • Logistic regression models assessed the association between BMI and self-reported, medically validated CCDs.

Main Results:

  • Higher BMI was associated with increased odds of CCDs (OR = 1.19, 95% CI: 1.07-1.31).
  • Hypertension significantly modified this association (P for interaction <0.001), with a stronger link in hypertensive individuals (OR = 1.28, 95% CI: 1.14-1.42).
  • Age, sex, and diabetes did not modify the BMI-CCD relationship.

Conclusions:

  • Higher BMI is linked to increased odds of CCDs, particularly in hypertensive patients.
  • Weight management strategies may be crucial for reducing CCD risk in individuals with hypertension.

Keywords:
body mass indexcardiovascular and cerebrovascular diseaseshypertension

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