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Peptichemio, teniposide and high-dose dexamethasone: a new active combination for relapsing and refractory multiple
A Zaniboni1, E Simoncini, P Marpicati
1IIIa Divisione Medicina Generale, Servizio di Oncologia, Fondazione Beretta, Spedali Civili, Brescia, Italy.
Anticancer Research
|January 1, 1988
Abstract:
Twelve patients with refractory (8 pts) and relapsing (4 pts) myeloma were treated with Peptichemio. Teniposide and high-dose dexamethasone. Eight patients experienced an objective response (5 out 8 with refractory and 3 out 4 with relapsing disease) with a median duration of 10+ months. Overall toxicity was mild to moderate and chiefly haematological. Our preliminary results seem very promising and justify a larger phase II study with this regimen.