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Related Concept Videos

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The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
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Related Experiment Video

Updated: Nov 17, 2025

Controlled Odor Mimic Permeation Systems for Olfactory Training and Field Testing
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Controlled Odor Mimic Permeation Systems for Olfactory Training and Field Testing.

Lauryn E DeGreeff1, Alison G Simon2, Michael S Macias3

  • 1Chemistry Division, US Naval Research Laboratory; International Forensic Research Institute, Florida International University; lauryn.degreeff@nrl.navy.mil.

Journal of Visualized Experiments : Jove
|February 15, 2021
PubMed
Summary

The Controlled Odor Mimic Permeation System (COMPS) offers a reproducible method for delivering controlled odorants. This system is valuable for olfactory testing and training, ensuring consistent scent release for various applications.

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Area of Science:

  • Analytical Chemistry
  • Materials Science

Background:

  • Controlled odor delivery is crucial for olfactory research and training.
  • Existing methods may lack convenience, reproducibility, or controlled release rates.

Purpose of the Study:

  • To introduce the Controlled Odor Mimic Permeation System (COMPS) as a novel solution for controlled odorant delivery.
  • To highlight the system's design, functionality, and applications in olfactory science.

Main Methods:

  • COMPS utilizes an odorant within a permeable polymer bag, double-contained for vapor equilibration.
  • Odorant release is controlled by bag material properties (thickness, surface area, polymer type).
  • Permeation rate is measured gravimetrically; concentration is assessed via SPME-GC/MS.

Main Results:

  • COMPS provides a convenient and reproducible method for odorant release.
  • The system allows for adjustable permeation rates tailored to specific needs.
  • COMPS can contain diverse odorants, including those relevant to detection training.

Conclusions:

  • COMPS offers a reliable and versatile tool for controlled odorant delivery in research and training.
  • The system's design ensures consistent and reproducible odor vapor generation.
  • COMPS advancements facilitate improved olfactory testing and canine detection training.