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Home-based multimodal exercise program in older people with Alzheimer disease: Randomized controlled trial protocol
Natália Oiring de Castro Cezar1, Juliana Hotta Ansai2, Larissa Pires de Andrade1
1Department of Physical Therapy, Federal University of São Carlos (UFSCar), São Carlos, São Paulo, Brazil.
Summary
Home-based exercise programs can improve muscle strength, balance, and cognition in older adults with Alzheimer disease (AD). This study investigated the effects of a 16-week multimodal exercise intervention on various health outcomes for individuals with AD.
Area of Science:
- Gerontology
- Neurology
- Exercise Science
Background:
- At-home physical exercise is a feasible intervention for older adults with Alzheimer disease (AD).
- Home-based programs offer enhanced adherence and convenience for caregivers.
- Multimodal exercise may address multiple facets of AD-related decline.
Purpose of the Study:
- To evaluate the impact of a home-based multimodal exercise program on older adults with AD.
- Assess effects on muscle strength, balance, functioning, cognition, dual-task performance, frailty, and physical activity levels.
- Provide evidence for clinical interventions and health promotion in AD.
Main Methods:
- A randomized trial involving 40 older adults with mild to moderate AD.
- Intervention group (IG) performed 16 weeks of home-based multimodal exercise (60 min, 3x/week).
- Control group (CG) received no intervention; both groups assessed by blinded examiners at baseline and 16 weeks.
Main Results:
- The study design anticipates improvements in the intervention group compared to the control group.
- Comprehensive assessments included measures of functioning, strength, frailty, cognition, balance, dual-task, and physical activity.
- Specific outcome measures utilized a range of validated tests and questionnaires.
Conclusions:
- Home-based multimodal exercise is expected to yield positive outcomes for older adults with AD.
- The findings will support the development of targeted interventions and health promotion strategies.
- This research provides a foundation for integrating exercise into AD care.
