Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Heart Failure VII: Nursing Interventions01:30

Heart Failure VII: Nursing Interventions

242
The first step in nursing management of a patient with heart failure involves thoroughly assessing the patient's medical history.Subjective Data: Obtain the patient's medical history of coronary artery disease, hypertension, myocardial infarction, and symptoms like dyspnea, orthopnea, and paroxysmal nocturnal dyspnea.Objective Data: Conduct a physical examination to identify findings such as jugular vein distention, pulmonary crackles, tachycardia, murmurs, peripheral edema, and vital signs,...
242
Drug Dosing: Geriatric Patients01:15

Drug Dosing: Geriatric Patients

102
Elderly individuals encompass a diverse population with varying degrees of age-related physiological changes. Defining the elderly presents challenges, as the geriatric population is often arbitrarily categorized as individuals older than 65. However, many individuals in this group lead active and healthy lives, with an increasing number surpassing 85 years and falling into the older elderly category. Physiological changes associated with aging impact performance capacity and homeostatic...
102
Pharmacodynamics in Geriatric Patients: Effects of Age01:27

Pharmacodynamics in Geriatric Patients: Effects of Age

93
Age-related pharmacokinetic changes are extensively documented, but understanding age-related pharmacodynamic alterations is relatively limited. This knowledge gap can be partly attributed to the complexity of developing appropriate measures of drug responses compared to bioanalytical methods for determining drug concentrations.Most information regarding age-related differences in human pharmacodynamics originates from cross-sectional studies. However, these studies assume that observed mean...
93
Cardiomyopathy VI: Nursing Management01:29

Cardiomyopathy VI: Nursing Management

147
Assessment: Nursing management of patients with cardiomyopathy begins with a thorough assessment of the patient's history, including a family history of cardiomyopathy or sudden cardiac death, personal history of heart disease, hypertension, diabetes, and any alcohol consumption or drug use.During the physical examination, assess vital signs, look for signs of heart failure (such as edema, jugular venous distention, and cyanosis), auscultate for abnormal heart sounds (like murmurs and gallops),...
147
Heart Failure V: Medical Management01:30

Heart Failure V: Medical Management

89
Medical Management of Acute Decompensated Heart Failure (ADHF)The primary goals of therapy for patients hospitalized with acute decompensated heart failure (ADHF) include:Relieving symptomsOptimizing volume statusSupporting oxygenation and ventilationMaintaining cardiac output (CO) and end-organ perfusionIdentifying and addressing the cause of ADHFPreventing complicationsProviding patient education on factors precipitating HF exacerbationPlanning for dischargeOngoing monitoring and assessment...
89
Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion01:18

Pharmacokinetics in Geriatric Patients: Effect of Age on Drug Excretion

143
In geriatric patients, renal physiology undergoes significant changes, including diminished renal blood flow and a lower glomerular filtration rate (GFR), leading to alterations in medication clearance. Drugs such as aminoglycoside antibiotics, lithium, and digoxin, which rely on glomerular filtration for removal from the body, particularly impact pharmacokinetics. These drugs tend to have slower clearance rates in older adults, necessitating careful dosage considerations.Evaluation of renal...
143

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Aortic arch replacement with descending thoracic aorta stenting for chronic dissection: early outcomes.

Journal of cardiothoracic surgery·2026
Same author

Frailty Modifies the Prognostic Effect of Age Among Older Adults With Acute Coronary Syndrome.

Journal of the American Heart Association·2025
Same author

Enhancing Osteoporosis Screening in High-Risk Men Ages 50 Years and Older: A Clinical Decision Support and Workflow Integration Approach.

Journal of primary care & community health·2025
Same author

Learning to see in the gray: Strategies for building critical analysis skills in the new ambulatory care practitioner.

American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists·2025
Same author

Implementation of Artificial Intelligence in Writing Letters of Recommendation.

Cureus·2025
Same author

Frailty Assessment and Outcomes During a COVID-19 Outbreak in a Long-Term Care Facility: The FRAIL-LTCF Scale.

Journal of the American Medical Directors Association·2025

Related Experiment Video

Updated: Nov 17, 2025

Frailty Assessment in an Aging Mouse Model
06:58

Frailty Assessment in an Aging Mouse Model

Published on: September 23, 2025

189

Frailty: Evaluation and Management.

Robert Allison1, Shauna Assadzandi1, Megan Adelman1

  • 1West Virginia University, Morgantown, WV, USA.

American Family Physician
|February 15, 2021
PubMed
Summary

Frailty is a geriatric syndrome increasing older adults' vulnerability to adverse outcomes like falls and disability. Early identification and individualized management, including exercise or palliative care, are crucial for frail individuals.

Area of Science:

  • Gerontology
  • Geriatric Medicine
  • Public Health

Background:

  • Frailty is a geriatric syndrome affecting 5-17% of older adults, characterized by increased vulnerability and leading to adverse health outcomes.
  • It is often overlooked or misdiagnosed as normal aging due to variable presentation and symptoms like weakness, exhaustion, and slow gait.
  • Frail older adults face higher risks of falls, disability, hospitalization, and mortality.

Purpose of the Study:

  • To highlight the significance of frailty as a geriatric syndrome.
  • To discuss the challenges in frailty diagnosis and the importance of comprehensive assessment.
  • To outline individualized management strategies for frail older adults.

Main Methods:

  • Review of frailty characteristics, symptoms, and diagnostic approaches.

More Related Videos

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
05:53

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

Published on: July 24, 2013

16.8K
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

901

Related Experiment Videos

Last Updated: Nov 17, 2025

Frailty Assessment in an Aging Mouse Model
06:58

Frailty Assessment in an Aging Mouse Model

Published on: September 23, 2025

189
Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty
05:53

Measuring Frailty in HIV-infected Individuals. Identification of Frail Patients is the First Step to Amelioration and Reversal of Frailty

Published on: July 24, 2013

16.8K
Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles
04:00

Author Spotlight: Assessing Surgical Frailty with Point-of-Care Ultrasound of Quadriceps Muscles

Published on: July 26, 2024

901
  • Discussion of validated frailty assessment tools and patient categorization (not-frail, prefrail, frail).
  • Exploration of individualized management based on frailty severity and patient goals.

    • Main Results:

    • Frailty presents with varied symptoms including weakness, exhaustion, slow gait, poor balance, and cognitive impairment.
    • Comprehensive geriatric assessment and validated tools aid in identifying and evaluating frailty.
    • Patients with more frail attributes exhibit higher risks of poor health outcomes.

    Conclusions:

    • Frailty management requires individualization, considering patient goals and life expectancy.
    • Physical activity and balance exercises are beneficial for less frail individuals.
    • Palliative care and symptom management are appropriate for more frail patients.