Related Experiment Video
Updated: Nov 17, 2025

Multiscale Sampling of a Heterogeneous Water/Metal Catalyst Interface using Density Functional Theory and Force-Field Molecular Dynamics
Published on: April 12, 2019
Insight into the Selective Methylene Oxidation Catalyzed by Mn(CF3-PDP)(SbF6)2/H2O2/CH2ClCO2H) System: A DFT
Ruihua Zhao1, Xiang-Yu Chen1, Zhi-Xiang Wang1
1School of Chemical Sciences, University of the Chinese Academy of Sciences, Beijing 100049, China.
Abstract:
DFT study was employed to gain insight into methylene oxidation catalyzed by Mn(CF3-PDP)(NCMe)2 (SbF6)2/H2O2/HOAcCl(OACCl ═OC(O)CH2Cl). The active catalyst was characterized to be [Mn](O)OAcCl ([Mn]═Mn(CF3-PDP)2+) which is generated via a sequence from [Mn] to [Mn]OH to [Mn]OAcCl to [Mn]OOH. With the active catalyst, the methylene group is sequentially oxidized to an alcohol and then to a carbonyl group via rebound mechanism. The mechanism explains the observed site selectivity.
More Related Videos
19:58Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
Published on: July 30, 2017
08:25Development of Heterogeneous Enantioselective Catalysts using Chiral Metal-Organic Frameworks MOFs
Published on: January 17, 2020
Related Concept Videos
Radical Oxidation of Allylic and Benzylic Alcohols
Oxidation of Alkenes: Syn Dihydroxylation with Potassium Permanganate
Oxidation of Alkenes: Syn Dihydroxylation with Osmium Tetraoxide
Radical Anti-Markovnikov Addition to Alkenes: Overview
Oxidation of Alcohols
The process of oxidation in a chemical reaction is observed in any of the three forms:
Regioselectivity of Electrophilic Additions-Peroxide Effect