[Ultrastructure of neuromuscular synapses during administration of dexamethasone]

Dexamethasone administration to rats at a dose of 100 micrograms/100 g body weight for 10 days resulted in the appearance of large synaptic vesicles in axon terminals, migration of synaptic vesicles to synaptic slits, local broadening of synaptic slit, proliferation of mitochondria in pre- and postsynaptic zones of the axomuscular synapses, destruction of myofibrils and other organelles in the postsynaptic area and the presence of lysosomes in this region.