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Cardiovascular health and chronic axonal polyneuropathy: A population-based study
Noor E Taams1,2, Fariba Ahmadizar1, Rens Hanewinckel2
1Department of Epidemiology, Erasmus University Medical Center, Rotterdam, The Netherlands.
European Journal of Neurology
|February 16, 2021
Summary
Better cardiovascular health is linked to a lower risk of chronic axonal polyneuropathy. Maintaining optimal cardiovascular health, including lifestyle and biological factors, may help prevent this nerve condition.
Area of Science:
- Neurology
- Cardiology
- Public Health
Background:
- Chronic axonal polyneuropathy is a prevalent neurological disorder with no current treatments.
- Its multifactorial nature necessitates exploring associated health conditions.
Purpose of the Study:
- To investigate the association between cardiovascular health and chronic axonal polyneuropathy.
- To determine if cardiovascular health score, as defined by the American Heart Association, correlates with polyneuropathy prevalence.
Main Methods:
- Utilized data from the Rotterdam Study, a population-based cohort (June 2013-January 2017).
- Assessed 1919 participants for polyneuropathy and calculated their cardiovascular health score (0-14) based on behaviors and factors.
- Categorized polyneuropathy as none, possible, probable, or definite.
Main Results:
- A higher cardiovascular health score was significantly associated with a lower prevalence of definite polyneuropathy (OR 0.90, 95% CI 0.84-0.96).
- Optimal cardiovascular health (score ≥10) showed a strong inverse relationship with polyneuropathy (OR 0.55, 95% CI 0.32-0.90).
- Both improved health behaviors and health factors independently correlated with reduced polyneuropathy risk.
Conclusions:
- Enhanced cardiovascular health, encompassing both lifestyle choices and physiological factors, is linked to a reduced prevalence of chronic axonal polyneuropathy.
- These findings suggest that improving cardiovascular health may be a viable strategy for polyneuropathy prevention.
Keywords:
American Heart Associationcardiovascular healthlifestylemetabolic syndromeneuropathypolyneuropathyMore Related Videos
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