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Are there gender differences in blood oxygen saturation in prepubertal children?
Zev Frimer1, Shmuel Goldberg1, Leon Joseph1
1Pediatric Pulmonary Institute, Shaare Zedek Medical Center, Affiliated with The Hebrew University, School of Medicine, Jerusalem, Israel.
Introduction:
Previous studies reported higher oxygen saturation (SpO2 ) in healthy young adult females as compared to males. The objective of the current study was to evaluate whether or not similar differences exist in prepubertal children.
Methods:
SpO2 levels, respiratory rate, and pulse were measured in 4- to 10-year-old males and females. Anthropometric variables, including ethnic origin, age, height, weight, BMI (Body Mass Index), BSA (Body Surface Area), barometric pressure, and altitude above sea level were collected as well.
Results:
Ninety five males and 93 females participated in the study. Groups were similar, in terms of respiratory rate, pulse, and anthropometric variables. Mean SpO2 in males was 96.95 ± 1.09%, similar to SpO2 in females measuring 96.85 ± 0.98%, P = .52.
Conclusion:
In contrast to young adults, there is no gender-related difference in mean oxygen saturation in prepubertal healthy children. It is likely that this difference is due to variations in age-related sex hormones. Further studies are needed to explore the mechanism explaining why prepubertal children do not show gender-specific differences in oxygen saturation in contrast to adults.
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