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Palmoplantar Involvement in Leprosy: A Clinicopathological Study
Garima Dabas1, Tarun Narang1, Sunil Dogra1
11Department of Dermatology, Venereology and Leprology, Postgraduate Institute of Medical Education and Research (PGIMER), Chandigarh, India.
The American Journal of Tropical Medicine and Hygiene
|February 16, 2021
Summary
Palmoplantar involvement in leprosy, though rare, is often misdiagnosed. This condition increases the risk of lepra reactions and disabilities, highlighting the need for increased clinical suspicion.
Area of Science:
- Dermatology
- Infectious Diseases
- Public Health
Background:
- Palmoplantar involvement in leprosy is infrequently documented and prone to misdiagnosis.
- Early identification is crucial for effective management and preventing complications.
Purpose of the Study:
- To analyze the prevalence, clinical presentation, and outcomes of palmoplantar involvement in leprosy patients.
- To assess the association between palmoplantar involvement and lepra reactions or disabilities.
Main Methods:
- Retrospective analysis of a leprosy clinic database from 2015 to 2018.
- Inclusion of 520 leprosy patients, with detailed examination of those exhibiting palmoplantar symptoms.
Main Results:
- Palmoplantar involvement was observed in 9.4% (49/520) of patients.
- Isolated palm involvement was most common (53.1%), followed by combined palm and sole (24.5%) and sole-only (22.4%) involvement.
- Patients with palmoplantar involvement showed a significantly higher incidence of lepra reactions and disabilities (P < 0.0001).
Conclusions:
- Palmoplantar involvement in leprosy, while uncommon, is a significant indicator of increased risk for reactions and disabilities.
- Maintaining a high index of suspicion for palmoplantar manifestations is essential to reduce leprosy misdiagnosis and improve patient outcomes.
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