Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Concept Videos

Development of Antibiotic Resistance01:30

Development of Antibiotic Resistance

793
Antibiotic resistance is a major public health concern that arises when bacteria evolve mechanisms to withstand the effects of antibiotic treatments. This resistance can be intrinsic, acquired through genetic mutations, or transferred between bacteria via horizontal gene transfer. The development of antibiotic resistance poses significant challenges in treating bacterial infections and necessitates ongoing research to develop new therapeutic strategies.Intrinsic resistance occurs when bacterial...
793
Antimicrobial Effectiveness01:28

Antimicrobial Effectiveness

756
The effectiveness of antimicrobial agents depends on various factors influencing their ability to eliminate microbial populations. Larger microbial populations require more time for complete eradication, emphasizing the importance of population size analysis when evaluating antimicrobial efficacy.Microbial resistance to antimicrobial agents varies significantly. Highly resilient microorganisms include endospores, gram-negative bacteria, and non-enveloped viruses, while prions are exceptionally...
756
Antibiotic Selection00:57

Antibiotic Selection

57.4K
Overview
57.4K
Healthcare Associated Infections II: Preventive Measures01:22

Healthcare Associated Infections II: Preventive Measures

3.4K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
3.4K
Combined Effects of Drugs: Synergism01:27

Combined Effects of Drugs: Synergism

5.8K
Synergism is a useful mechanism where combining two or more drugs is more effective than each constituent used alone. Such combinations are also called supra-additive interactions. The drugs collectively enhance the final therapeutic effect by acting on different targets. Another advantage is that the low dose of each constituent drug is sufficient to achieve the desired effect. This helps reduce the duration of therapy and lower the adverse effects of these drugs.
Such synergistic combinations...
5.8K
Antimicrobial Proteins01:23

Antimicrobial Proteins

12.4K
Antimicrobial proteins are important components of the immune system. They aid the body in combating pathogens by either killing them directly or hindering their replication processes. Four main types of antimicrobial substances are interferons, the complement system, iron-binding proteins, and antimicrobial proteins.
Interferons
Interferons (IFNs) are proteins produced by lymphocytes, macrophages, and fibroblasts infected with viruses. While IFNs cannot prevent viruses from entering and...
12.4K

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Response to: "best practices when benchmarking CATCH for the design of genome enrichment probes".

Bioinformatics (Oxford, England)·2026
Same author

Enriched Long-Read Sequencing of Co-circulating Viruses in Complex Samples.

Molecular biology and evolution·2025
Same author

Assessment of a program for monitoring antimicrobial purchase and resistance in <i>Escherichia coli</i> and <i>Salmonella enterica</i> on pig farms in the Midwestern United States from May 2020 through October 2023.

Frontiers in veterinary science·2025
Same author

Reducing skin microbiome exposure impacts through swine farm biosecurity.

GigaScience·2025
Same author

The impact of pooling on the observed microbiome profile of preweaned piglet feces.

FEMS microbiology ecology·2025
Same author

Salmonella enterica Serovar Abony Outbreak Caused by Clone of Reference Strain WDCM 00029, Chile, 2024.

Emerging infectious diseases·2024

Related Experiment Video

Updated: Nov 17, 2025

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

1.3K

Beyond Antimicrobial Use: A Framework for Prioritizing Antimicrobial Resistance Interventions.

Noelle R Noyes1, Ilya B Slizovskiy1, Randall S Singer2

  • 1Department of Veterinary Population Medicine, College of Veterinary Medicine, University of Minnesota, St. Paul, Minnesota 55108, USA; email: nnoyes@umn.edu, slizo001@umn.edu.

Annual Review of Animal Biosciences
|February 16, 2021
PubMed
Summary

Antimicrobial resistance (AMR) is a growing threat. Reducing antimicrobial use shows variable success, prompting a need to broaden interventions beyond just usage to include host-microbial factors and environmental influences.

Keywords:
antimicrobial resistanceantimicrobial useframeworklivestock

More Related Videos

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

7.2K
Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

1.6K

Related Experiment Videos

Last Updated: Nov 17, 2025

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics
06:54

Author Spotlight: Understanding and Detecting Environmental Antimicrobial Resistance by Combining Culture-Based Techniques and Genomics

Published on: July 19, 2024

1.3K
Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes
08:58

Isolation and Identification of Waterborne Antibiotic-Resistant Bacteria and Molecular Characterization of their Antibiotic Resistance Genes

Published on: March 3, 2023

7.2K
Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance
09:59

Application of the Intelligent High-Throughput Antimicrobial Sensitivity Testing/Phage Screening System and Lar Index of Antimicrobial Resistance

Published on: July 21, 2023

1.6K

Area of Science:

  • One Health
  • Microbiology
  • Epidemiology

Background:

  • Antimicrobial resistance (AMR) poses a significant threat to both animal and human health.
  • Antimicrobial use is a primary driver of AMR, leading to widespread implementation of antimicrobial stewardship programs.
  • Current interventions focused on reducing antimicrobial use have shown variable effectiveness in combating AMR.

Purpose of the Study:

  • To propose a novel framework for prioritizing AMR interventions.
  • To evaluate the impact of interventions targeting antimicrobial use within this framework.
  • To advocate for an expanded approach to AMR intervention strategies.

Main Methods:

  • Development of a prioritization framework for AMR interventions.
  • Evaluation of existing interventions focused on reducing antimicrobial use.
  • Analysis of non-antibiotic factors influencing AMR across diverse systems.

Main Results:

  • Interventions solely focused on reducing antimicrobial use have yielded inconsistent results in mitigating AMR.
  • Scientific advancements highlight the complex interplay of non-antibiotic factors in driving AMR.
  • The effectiveness of interventions varies significantly based on system, geography, and context.

Conclusions:

  • A broader approach to AMR interventions is necessary, moving beyond solely antimicrobial use reduction.
  • Prioritization should incorporate host-microbial interactions that influence AMR development.
  • Anthropogenic and environmental systems that facilitate AMR dissemination require greater consideration in intervention strategies.