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Updated: Aug 2, 2026

Analysis of Dendritic Spine Morphology in Cultured CNS Neurons
Published on: July 13, 2011
Dendritic spines are susceptible to structural alterations induced by degeneration of their presynaptic afferents
1Unit of Morphology, Corob Center for Health Sciences, Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer Sheva, Israel.
Abstract:
The shape of dendritic spines in mouse Sm1 cortex, which synapse with degenerating thalamocortical axon terminals, differs significantly from that of adjacent spines along the same spiny dendrites, which synapse with intact axon terminals. It is concluded that this morphological difference results from focal alterations in the heads of spines imposed by the degeneration of their presynaptic afferents.
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