Malignant adenomyoepithelioma of the breast: A case report
Zhihao Zhang1, Yueyuan Wang1, Xiao Xie1
1Department of Breast Surgery.
Rationale:
Adenomyoepithelioma (AME) is a rare biphasic tumor consisting of epithelial and Myoepithelial cell. Most of the AME is benign, and only a few will progress to malignancy, Here, we report a case of low-grade malignant adenomyoepithelioma, and review the related literature, in a bid to investigate its clinical and pathological features and thus, enhance our understanding of this tumor.
Patient Concerns:
A 64-year-old woman visited our hospital with a 1-year history of a painless mass in her left breast. Physical examination revealed a palpable painless mass, measuring approximately 4.5 cm, in the left breast.
Diagnosis:
Histological examination confirmed the diagnosis of malignant adenomyoepithelioma.
Interventions:
The patient underwent local excision of the mass, with frozen section analysis revealing ductal carcinoma in situ. Mastectomy and sentinel lymph node biopsy were then performed.
Outcomes:
We conducted a one-year follow-up, and relapse was not observed.
Lessons:
Treatment of AME remains controversial owing to the lack of high volume data and absence of prospective studies. Simple mastectomy is an acceptable treatment of this tumor.
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