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Labial salivary gland tumors
B W Neville1, D D Damm, J C Weir
1Department of Diagnostic Science, College of Dental Medicine, Medical University of South Carolina, Charleston 29425.
Cancer
|May 15, 1988
Summary
Labial salivary gland tumors are more common in the upper lip, but lower lip tumors show a higher malignancy rate. This study analyzed 103 tumors, finding upper lip tumors predominantly benign and lower lip tumors mostly malignant.
Area of Science:
- Oral Pathology
- Oncology
- Salivary Gland Neoplasms
Background:
- Minor salivary gland tumors represent a diverse group of neoplasms.
- Labial salivary glands are a common site for minor salivary gland tumors.
- Understanding the distribution and behavior of these tumors is crucial for diagnosis and treatment.
Purpose of the Study:
- To analyze the incidence and histological types of tumors affecting the upper and lower labial salivary glands.
- To compare the prevalence and malignant potential of tumors in the upper versus lower lip.
- To contribute to the existing knowledge base on minor salivary gland neoplasms.
Main Methods:
- Retrospective analysis of 103 labial salivary gland tumors from four oral pathology laboratories.
- Classification of tumors based on location (upper vs. lower lip) and histopathological diagnosis.
- Statistical analysis of tumor distribution, frequency, and malignancy rates.
Main Results:
- A total of 103 tumors were identified: 87 (84.5%) in the upper lip and 16 (15.5%) in the lower lip.
- Upper lip tumors were predominantly benign (92.0%), with monomorphic adenomas and pleomorphic adenomas being most common.
- Lower lip tumors were predominantly malignant (93.8%), with mucoepidermoid carcinomas being the most frequent type.
Conclusions:
- Minor salivary gland tumors exhibit a distinct topographical predilection, favoring the upper lip.
- Tumors of the lower lip possess a significantly higher likelihood of being malignant compared to upper lip tumors.
- These findings underscore the importance of considering lip location in the assessment of salivary gland neoplasms.