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A case report on transient cardiomyopathy with cytokine storm in SARS-CoV-2
Tushar Tarun1,2, Senthil Kumar1,2, Jeremy Johnson3
1Division of Cardiovascular Medicine, University of Missouri-Columbia, 1 hospital Drive, CE 306, Columbia, MO 65201, USA.
Background:
Cardiac manifestations during Severe Acute Respiratory Syndrome Corona Virus 2 (SARS-CoV-2) pandemic have included acute coronary syndrome, arrhythmias, myocarditis, and stress cardiomyopathy. However, the combination of cardiomyopathy and negative cardiac biomarkers has not yet been reported.
Case Summary:
A 49-year-old man admitted for respiratory failure secondary to SARS-CoV-2 developed new-onset cardiomyopathy with negative cardiac biomarkers. Left ventricular ejection fraction and strain improved 7 days after the initial echocardiogram, after administration of Tocilizumab, coinciding with clinical recovery, and improvement in inflammatory markers.
Discussion:
As experience of cardiovascular manifestations of SARS-CoV-2 increases, more patients will likely present with cardiovascular manifestations; the recognition and proper management of these may improve patient outcomes.
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