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Updated: Nov 17, 2025

Palladium N-Heterocyclic Carbene Complexes: Synthesis from Benzimidazolium Salts and Catalytic Activity in Carbon-carbon Bond-forming Reactions
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A predictive model for additions to N-alkyl pyridiniums

Brian J Knight1, Zachary A Tolchin1, Joel M Smith1

  • 1Department of Chemistry and Biochemistry, Florida State University, 95 Chieftan Way, Tallahassee, FL 32306, USA. smith@chem.fsu.edu.

Chemical Communications (Cambridge, England)
|February 17, 2021
PubMed
Summary

This study details the dearomative addition of organomagnesium nucleophiles to pyridinium electrophiles, revealing predictable regiochemical trends based on substituent patterns. These findings enable selective synthesis, including insecticidal compounds.

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