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Giant spotted grouped pigmented nevus: A case report
Hussein M M Hassab-El-Naby1, Mohamed Amer1, Mahmoud A Rageh1
1Department of Dermatology, Faculty of Medicine, Al-Azhar University, Cairo, Egypt.
Journal of Cutaneous Pathology
|February 17, 2021
Summary
Spotted grouped pigmented nevus, a rare non-giant congenital melanocytic nevus, can present as a giant form. This case highlights a 10-year-old boy with a nevus exceeding 20 cm.
Area of Science:
- Dermatology
- Pathology
Background:
- Congenital melanocytic nevi (CMN) are common benign melanocyte proliferations.
- Spotted grouped pigmented nevus (SGPN) is a specific subtype of non-giant CMN.
- SGPN typically shows proliferation around skin appendages.
Observation:
- A 10-year-old boy presented with a large pigmented skin lesion.
- The lesion measured over 20 cm in diameter.
- Clinical and pathological findings confirmed SGPN.
Findings:
- The patient's SGPN was histopathologically confirmed.
- The size of the nevus ( > 20 cm) qualified it as giant.
- This presentation is unusual for the typically non-giant SGPN subtype.
Implications:
- This case expands the known clinical spectrum of SGPN.
- It underscores the importance of considering giant forms even in rare nevus subtypes.
- Further research may clarify the pathogenesis of giant SGPN.

