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Using constant-wavelength synchronous fluorescence spectroscopy in nanoparticle-based sensors: a minireview
Abolghasem Jouyban1, Elaheh Rahimpour
1Pharmaceutical Analysis Research Center, Faculty of Pharmacy, Tabriz University of Medical Sciences, Tabriz, Iran. rahimpour_e@yahoo.com.
Analytical Methods : Advancing Methods and Applications
|February 17, 2021
Summary
This review explores optical nanosensors utilizing constant-wavelength synchronous fluorescence spectroscopy (SFS) for enhanced analytical selectivity. It categorizes SFS nanosensors by detection mechanisms, highlighting their applications over recent decades.
Area of Science:
- Analytical Chemistry
- Spectroscopy
- Nanotechnology
Background:
- Conventional fluorescence spectroscopy suffers from spectral complexity and lower selectivity.
- Synchronous fluorescence spectroscopy (SFS) offers improved spectral resolution and simplification.
- Nanosensors provide enhanced sensitivity and specificity for various analytical applications.
Purpose of the Study:
- To review optical nanosensors based on constant-wavelength synchronous fluorescence spectroscopy (SFS).
- To explore the applications of SFS-based nanosensors in analytical chemistry over the past few decades.
- To classify SFS nanosensors based on their analyte detection mechanisms.
Main Methods:
- Comprehensive literature review of SFS-based nanosensor studies.
- Classification of nanosensors based on quenching and enhancement detection mechanisms.
- Tabulation of analytical properties for reported SFS nanosensors.
Main Results:
- SFS demonstrates superior selectivity compared to conventional fluorescence due to spectral narrowing.
- SFS-based nanosensors are categorized into quenching and enhancement types.
- Detailed review and tabulation of analytical properties for numerous SFS nanosensor studies.
Conclusions:
- SFS-based optical nanosensors offer significant advantages in analytical selectivity and spectral simplification.
- The review provides a comprehensive overview and classification of SFS nanosensors and their applications.
- This work aims to encourage further research and development in SFS nanosensor technology.

