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Multidisciplinary Approach to Obesity Management: A Case Report
Published on: May 30, 2025
650
Long-Term Weight Loss Strategies for Obesity
Karim Kheniser1, David R Saxon2, Sangeeta R Kashyap3
1Center for Neurological Restoration, Cleveland Clinic, Cleveland, OH, USA.
The Journal of Clinical Endocrinology and Metabolism
|February 17, 2021
Summary
Obesity management requires a holistic approach, combining lifestyle changes, behavioral therapy, medication, and surgery. A multidisciplinary team and maintenance programs are key to long-term success and reducing disease risk.
Area of Science:
- Endocrinology
- Metabolic Diseases
- Public Health
Background:
- Obesity is a complex, chronic disease demanding comprehensive management strategies.
- Current therapeutic options include lifestyle modification, cognitive behavioral therapy, pharmacotherapy, and bariatric surgery.
Purpose of the Study:
- To review the evidence for various obesity treatment modalities.
- To outline effective strategies for long-term weight management and associated health risks.
Main Methods:
- Systematic review and consolidation of evidence from randomized controlled trials, observational studies, and meta-analyses.
- Analysis of short-term and long-term efficacy of different therapeutic interventions.
Main Results:
- Lifestyle interventions yield approximately 5% weight loss in 2 years, with benefits for type 2 diabetes and cardiovascular disease risk, despite potential weight regain.
- Bariatric surgery can achieve over 50% excess weight loss long-term, though weight regain is a concern.
- Multifactorial maintenance programs integrating diet, exercise, pharmacotherapy, and behavioral therapy are crucial for sustained weight loss.
Conclusions:
- Effective obesity management necessitates a multidisciplinary clinical team approach.
- Integrated therapies, including lifestyle, pharmacotherapy, and behavioral support, are essential for maintenance.
- Bariatric surgery is a vital option for select patients with type 2 diabetes and obesity.
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