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Updated: Nov 17, 2025

A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance
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A New Technique for Treating Low-risk Prostate Cancer—Super Active Surveillance

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246

Contemporary management of advanced prostate cancer: an evolving landscape

Abhinav Khanna1, Luke P O'Connor1, Prithvi B Murthy1

  • 1Glickman Urologic and Kidney Institute, Cleveland Clinic, Cleveland, Ohio.

Clinical Advances in Hematology & Oncology : H&O
|February 17, 2021
PubMed

Insights

Advanced and metastatic prostate cancer incidence is rising, prompting new treatments. This review offers clinicians a guide to the latest pharmaceutical and diagnostic advancements for managing advanced prostate cancer.

Area of Science:

  • Oncology
  • Urology

Background:

  • Population-based studies indicate a potential increase in advanced and metastatic prostate cancer incidence.
  • This trend coincides with significant advancements in treatment options for advanced prostate cancer.

Purpose of the Study:

  • To provide a clinical primer on managing advanced prostate cancer.
  • To review recent developments in pharmaceuticals and diagnostics for advanced prostate cancer.

Main Methods:

  • Literature review of recent population-based studies.
  • Overview of novel pharmaceutical approvals and diagnostic tool evolution.

Main Results:

  • Eight novel agents have been approved by the US Food and Drug Administration in the past decade.
  • Rapid advancements in diagnostic tools for prostate cancer have emerged.

Conclusions:

  • Clinicians require updated knowledge to manage the rising incidence of advanced prostate cancer.
  • The review serves as a guide for medical oncologists, radiation oncologists, and urologists treating advanced prostate cancer.

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