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Published on: June 28, 2024
Pineal Region Meningioma in a Very Young Child
Chandrashekhar Gendle1, Madhivanan Karthigeyan2, Pravin Salunke1
1Department of Neurosurgery, Postgraduate Institute of Medical Education & Research (PGIMER), Chandigarh, India.
Insights
Pediatric pineal region meningiomas are rare. This case highlights a large meningioma in a 2.5-year-old, emphasizing early consideration for favorable outcomes with surgical resection.
Area of Science:
- Pediatric neurosurgery
- Pediatric oncology
- Neuroradiology
Background:
- Meningiomas are uncommon in children, with pineal location being exceptionally rare, especially in those under five years old.
- This report details a rare case of a large pineal region meningioma in a very young child.
- The tumor presented atypically, mimicking common pathologies found at this intracranial site.
Observation:
- A 2.5-year-old child presented with signs of increased intracranial pressure.
- Magnetic Resonance Imaging (MRI) revealed a homogeneously enhancing pineal lesion with small cystic components.
- Cerebrospinal fluid analysis was initially performed to rule out germ cell tumors.
Findings:
- Surgical excision via the Krause approach was performed.
- The tumor lacked clear dural attachment and had a distinct arachnoid plane.
- Histopathological examination confirmed the diagnosis of meningioma.
- Complete tumor resection was achieved.
Implications:
- Meningiomas should be considered in the differential diagnosis of pediatric pineal region lesions.
- Early recognition and complete resection are associated with favorable outcomes in pediatric meningiomas.
- Preoperative and intraoperative assessments, including frozen section analysis, aid in differentiating pineal region tumors and guiding surgical strategy.
Introduction:
Meningiomas in childhood are infrequently seen. Furthermore, they are extremely rare at a pineal location with few reported cases above 5-years of age. We present a very young child with a large pineal region meningioma which mimicked the usually occurring pathologies at this site.
Case Presentation:
A 2.5-year-old child presented with symptoms of raised intracranial pressure. MRI demonstrated a homogenously enhancing pineal lesion with small cystic areas. After an initial cerebrospinal fluid evaluation for germ cell tumors, the child underwent excision of the lesion by the Krause approach. The tumor showed no definitive dural attachment, had well-defined arachnoid interface, and was completely excised. The final histopathology was meningioma.
Conclusion:
Although unusual, we highlight the importance of considering meningiomas among the childhood pineal region lesions, given their good outcome with total resection. Also, pertinent brief literature of the pediatric pineal region meningiomas has been provided. An assessment of preoperative and intraoperative features (clear arachnoid plane) along with adjuncts such as frozen studies can help discern various entities of this region, and decide the extent of excision.
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