Related Experiment Video

Updated: Nov 17, 2025

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction
07:44

Endoscopic Ultrasound-Guided Biliary Drainage: Endoscopic Ultrasound-Guided Hepaticogastrostomy in Malignant Biliary Obstruction

Published on: March 25, 2022

6.2K

Outcomes of Endoscopic Ultrasound-Guided Biliary Drainage in Patients Undergoing Antithrombotic Therapy

Nozomi Okuno1, Kazuo Hara1, Nobumasa Mizuno1

  • 1Department of Gastroenterology, Aichi Cancer Center Hospital, Nagoya, Japan.

Clinical Endoscopy
|February 18, 2021
PubMed

Insights

Endoscopic ultrasound-guided biliary drainage (EUS-BD) has a low bleeding risk, even for patients on antithrombotic therapy. This study found no significant difference in bleeding events between patients receiving and not receiving antithrombotic agents during EUS-BD.

Area of Science:

  • Gastroenterology
  • Interventional Endoscopy
  • Oncology

Background:

  • Japan Gastroenterological Endoscopy Society (JGES) guidelines classify endoscopic ultrasound-guided biliary drainage (EUS-BD) as high-risk.
  • The bleeding risk of EUS-BD in patients on antithrombotic therapy remains uncertain.

Purpose of the Study:

  • To assess the bleeding risk of EUS-BD in patients undergoing antithrombotic therapy.
  • To compare bleeding event rates between patients receiving and not receiving antithrombotic agents during EUS-BD.

Main Methods:

  • Single-center retrospective study of 220 patients undergoing EUS-BD (January 2013 - December 2018).
  • Antithrombotic agent management followed JGES guidelines.
  • Bleeding event rates were compared between antithrombotic and non-antithrombotic groups.

Main Results:

  • Overall bleeding event rate was 1.3% (3/220).
  • One bleeding event (5.5%) occurred in the antithrombotic group (18 patients); two (0.9%) in the non-antithrombotic group (202 patients) (p=0.10).
  • All bleeding events were moderate; one thromboembolic event (cerebral infarction) occurred in the non-antithrombotic group.

Conclusions:

  • EUS-BD-related bleeding events occurred at a low rate.
  • Bleeding event rates in patients on antithrombotic therapy were not significantly different from those not on antithrombotic therapy.
Abstract

Keywords:
Anticoagulant agentsAntiplatelet agentsAntithrombotic agentsBleedingEUS-guided biliary drainage

More Related Videos

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy03:56

A Two-Step Method for Percutaneous Transhepatic Choledochoscopic Lithotomy

Published on: September 13, 2022

2.6K
Application of Laparoscopic Ultrasonography in Primary Choledochal Suture during Combined Two-lens Surgery04:03

Application of Laparoscopic Ultrasonography in Primary Choledochal Suture during Combined Two-lens Surgery

Published on: March 28, 2025

330

Related Concept Videos

Endoscopic Procedures V: ERCP01:26

Endoscopic Procedures V: ERCP

Endoscopic Retrograde Cholangiopancreatography (ERCP) is a diagnostic procedure that combines endoscopy and fluoroscopy to diagnose and treat conditions related to the bile ducts, pancreatic ducts, and gallbladder. This procedure is beneficial for identifying and addressing blockages, gallstones, strictures, and tumors within the biliary or pancreatic systems. ERCP is both diagnostic and therapeutic, offering the ability to visualize and treat identified problems in one session.
Patient...
1.5K
Venous Thrombosis III: Interprofessional Care01:29

Venous Thrombosis III: Interprofessional Care

Venous thrombosis requires effective prevention and treatment strategies to improve patient outcomes and reduce potential complications.Prevention StrategiesHealthcare providers must prioritize preventing venous thromboembolism (VTE) for all adult patients upon admission. Interventions depend on bleeding and thrombosis risk, medical history, current medications, diagnoses, planned procedures, and patient preferences. Patients on bed rest should change positions every two hours and, if not...
112
Esophageal Varices-II: Clinical Features and Management01:28

Esophageal Varices-II: Clinical Features and Management

Esophageal varices often manifest as gastrointestinal bleeding episodes, presenting symptoms like hematemesis (vomiting of blood), hematochezia (passing fresh blood via the rectum), and melena (black, tarry stools). Other signs can include weight loss, anorexia, abdominal discomfort, jaundice, pruritus, altered mental status, and muscle cramps.
In the initial assessment, a thorough review of the patient's medical history is vital to identify risk factors such as liver disease, alcohol...
233
Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care01:29

Pulmonary Embolism II: Diagnostic Studies and Interprofessional Care

Diagnosing Pulmonary EmbolismDiagnosing pulmonary embolism (PE) involves clinical assessment and advanced imaging tests. The preferred diagnostic tool is the spiral (helical) CT scan or CT angiography (CTA), which uses intravenous contrast media to visualize the pulmonary vasculature and identify emboli.A ventilation-perfusion (V/Q) scan is an alternative for patients unable to receive contrast media. This scan includes both perfusion and ventilation scanning. Perfusion scanning involves...
112
Endoscopic Studies II: Thoracocentesis01:26

Endoscopic Studies II: Thoracocentesis

Thoracentesis(Thoracocentesis), commonly known as pleural tap, is a medical procedure where a 22 gauge needle is inserted into the pleural space, the area between the lung and chest wall. This procedure is commonly performed to diagnose or treat various respiratory disorders.
Description
Excess pleural fluid or air may accumulate in some respiratory disorders in the thoracic cavity. To treat pleural effusion, a physician conducts thoracentesis by carefully piercing the chest wall and entering...
859
Ultrasound II: Endoscopic Ultrasound and FibroScan01:25

Ultrasound II: Endoscopic Ultrasound and FibroScan

Endoscopic Ultrasound (EUS) and FibroScan are valuable diagnostic tools in gastroenterology and hepatology, each with specific applications and techniques.
Endoscopic Ultrasound (EUS):
298