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A long-term double-blind controlled study on the effect of azathioprine in the treatment of multiple sclerosis
J M Minderhoud1, A J Prange, G J Luyckx
1Department of Neurology, University Hospital Groningen, the Netherlands.
Clinical Neurology and Neurosurgery
|January 1, 1988
Abstract:
The results are reported of a small double-blind controlled trial on the effect of azathioprine in multiple sclerosis. Although a trend in favour of the treated group, as regards the effect on the disability, was found, it did not reach statistical significant levels. No influence was found on the relapse rate. The influence of side-effects, which were found in the treated group in a higher percentage than in the placebo group, on the results is discussed.