[Application of Fluorescence Imaging to Liver Cancer Surgery]

Area of Science:

• Hepatobiliary Surgery
• Medical Imaging
• Surgical Oncology

Background:

• Intraoperative fluorescence imaging is crucial in hepatobiliary surgery.
• Techniques for identifying bile ducts, liver tumors, and liver segments are advancing.
• Indocyanine green (ICG) is a key fluorescent agent used in these procedures.

Purpose of the Study:

• To highlight the utility of intraoperative fluorescence imaging in hepatobiliary surgery.
• To discuss the application of indocyanine green (ICG) for real-time surgical guidance.
• To explore future therapeutic applications of ICG in liver cancer treatment.

Main Methods:

• Utilizing indocyanine green (ICG) for fluorescence cholangiography.
• Employing near-infrared imaging systems for open and laparoscopic surgery.
• Analyzing the biliary excretion and fluorescence properties of ICG.

Main Results:

• Real-time identification of extrahepatic bile ducts, liver cancers, and hepatic segmental boundaries is achievable.
• Advancement and global adoption of ICG-based fluorescence imaging in surgery.
• ICG accumulation in cancer tissues offers potential for targeted therapies.

Conclusions:

• Fluorescence imaging with ICG is a valuable tool in hepatobiliary surgery.
• The technique has seen significant development and worldwide adoption.
• ICG's properties may enable novel photodynamic therapies for liver cancers.