Related Experiment Video
Updated: Jul 30, 2026

In vivo Imaging of Transgenic Leishmania Parasites in a Live Host
Published on: July 27, 2010
Effects of some natural leads on Trypanosoma and Leishmania strains
A A M Alkhaldi1, H P De Koning2, S N A Bukhari3
1Biology Department, College of Science, Jouf University, Sakaka, Aljouf 2014, Saudi Arabia.
Abstract:
Well-known medical herbal compounds including apigenin, daidzein, phyllanthin and tyramine were assessed against Trypanosoma and Leishmania protozoans. Two strains of the bloodstream forms of Trypanosoma brucei: s427-WT and TbAT1-B48, and Leishmania major and Leishmania mexicana promastigotes were utilised. Among selected natural compounds, apigenin and daidzein displayed moderate activity against African trypanosomes with EC50 16 µM for wild-type sensitive control strain. Tyramine was not found to be very active for trypanosomes strains while all compounds were found to have trivial activity for the inhibition of Leishmania mexicana strains.
More Related Videos
10:01Quantification of Intracellular Growth Inside Macrophages is a Fast and Reliable Method for Assessing the Virulence of Leishmania Parasites
Published on: March 16, 2018
06:57In Vivo Infection with Leishmania amazonensis to Evaluate Parasite Virulence in Mice
Published on: February 20, 2020
Related Concept Videos
Leishmaniasis
American Trypanosomiasis
Antiprotozoal Agents