Related Experiment Video
Updated: Nov 17, 2025
09:58
Using Eggs from Schistosoma mansoni as an In vivo Model of Helminth-induced Lung Inflammation
Published on: June 5, 2012
14.1K
Multidisciplinary biomarkers aggrieve morbidity in schistosomiasis
1Medical Parasitology Department, College of Medicine, Cairo University, Cairo, Egypt.
Tropical Biomedicine
|February 18, 2021
Summary
Biomarkers like CRP and IgE indicate inflammation in early schistosomiasis, while hemoglobin and ferritin improve over time. Vitamin D deficiency persists throughout the disease course.
Area of Science:
- Parasitology
- Immunology
- Clinical Biochemistry
Background:
- Biomarkers are measurable indicators of pathological processes.
- Various biomarkers influence schistosomiasis morbidity in Egypt.
Purpose of the Study:
- To identify the relationship between CRP, IgE, hemoglobin, ferritin, vitamin D, and platelets with active and chronic schistosomiasis.
- To investigate demographic influences and interrelationships of these biomarkers.
Main Methods:
- Cross-sectional study involving 400 participants.
- Parasitological analysis, Indirect Hemagglutination Test, Enzyme linked Immunoassay, and Hematology Analyzer.
- Statistical analysis using SPSS version 25.
Main Results:
- 25% of participants had schistosomiasis (active or chronic).
- Higher CRP and IgE levels in active infections; lower hemoglobin in active, improving in chronic infections.
- Vitamin D was reduced in both active and chronic schistosomiasis; platelets remained normal.
Conclusions:
- Anemia correlates with inflammatory markers (CRP, IgE) in early schistosomiasis.
- Hemoglobin and ferritin levels improve during chronicity.
- Hypovitaminosis-D is associated with schistosomiasis throughout its course.
More Related Videos
Related Concept Videos
01:17Chronic Bowel Disorders: Introduction
633
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
633
01:24Chronic Kidney Disease II: Clinical Manifestations
316
Chronic Kidney Disease (CKD) progressively impairs multiple body systems due to the accumulation of uremic toxins, which disrupt cellular functions across various organs.Neurologic symptomsNeurologic symptoms often arise early in CKD, as uremic toxin buildup drives changes in cognitive and motor functions. Patients frequently experience fatigue, headache, confusion, difficulty concentrating, and, in severe cases, seizures. Peripheral neuropathy commonly manifests as burning sensations in the...
316
01:22Effect of Hepatic Disease on Pharmacokinetics: Pathophysiologic Assessment and Liver Function Test
76
In clinical practice, the direct measurement of hepatic blood flow to evaluate liver function presents significant challenges due to the intricate and specialized nature of the necessary techniques. Consequently, healthcare professionals often rely on empirical estimates derived from thorough patient examinations and liver function tests to gauge liver health. Among the tools at their disposal, the Child–Pugh and MELD scoring systems stand out for their ability to categorize and assess...
76