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Sudden death due to infective endocarditis caused by Streptococcus constellatus: A case report

M S Zamasry1, Z Hilmi1, M Y P Mohd Yusof2,3

  • 1National Institute of Forensic Medicine (IPFN), Hospital Kuala Lumpur, 50586 Kuala Lumpur, Malaysia.

Tropical Biomedicine
|February 18, 2021
PubMed

Insights

Infective endocarditis (IE) caused by Streptococcus constellatus can lead to sudden death. This case report details a rare instance of mortality from this infection, emphasizing the need for increased awareness and research into risk factors.

Area of Science:

  • Cardiology
  • Infectious Diseases
  • Forensic Pathology

Background:

  • Infective endocarditis (IE) presents diagnostic challenges, with increasing incidence and antibiotic resistance contributing to mortality.
  • Staphylococcus aureus is the most common cause, but a broader range of pathogens are emerging.
  • Sudden death can occur due to undiagnosed IE.

Observation:

  • This case report details a rare instance of sudden death attributed to IE caused by Streptococcus constellatus, a member of the Streptococcus anginosus group.
  • This pathogen is an uncommon cause of IE, particularly in the Malaysian forensic and clinical settings.
  • The report outlines the pathological features associated with this specific microorganism.

Findings:

  • Streptococcus constellatus, a rare pathogen, was identified as the cause of infective endocarditis leading to sudden death.
  • The incidence of IE varies globally, highlighting its significance as a public health concern.
  • This is the first reported case of sudden death due to Streptococcus constellatus IE in Malaysia.

Implications:

  • The emergence of diverse causative agents in IE necessitates enhanced diagnostic vigilance.
  • Further research into the risk factors associated with Streptococcus constellatus IE is crucial.
  • Improved understanding may lead to better prevention strategies and reduced morbidity and mortality from IE.

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