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CD8+CD161+ T-Cells: Cytotoxic Memory Cells With High Therapeutic Potential

Vanaja Konduri1, Damilola Oyewole-Said1, Jonathan Vazquez-Perez1

  • 1Department of Pathology & Immunology, Baylor College of Medicine, Houston, TX, United States.

Frontiers in Immunology
|February 18, 2021
PubMed
Summary

CD161-expressing CD8+ T cells, including MAIT and Tc17 cells, show enhanced cytotoxicity. This review explores their function and potential in fighting infections and cancer.

Keywords:
CD161KLRB1T-cellTH1 polarizationeffector memory

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