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Purulent pericarditis-induced intracardiac perforation and infective endocarditis due to Parvimonas micra: a case
Hiroaki Morinaga1, Ken Kato1, Motoyuki Hisagi2
1Department of Cardiology, Tokyo Metropolitan Tama Medical Center, Tokyo, Japan.
Background:
Purulent pericarditis, a rare disease with a high associated mortality rate in patients without adequate treatment, can cause serious complications, such as perforation of the surrounding tissue and organs. Parvimonas micra is a very rare cause of purulent pericarditis.
Case Summary:
A 70-year-old male patient presented to our emergency room with chest pain of 10 days' duration. An electrocardiogram showed ST-segment elevation and PR-segment depression on multiple leads. A transthoracic echocardiogram showed normal left ventricular function and a large amount of pericardial effusion. Acute pericarditis was diagnosed, and anti-inflammatory drug therapy was initiated. Due to the lack of improvement in the symptoms, pericardiocentesis was performed on Day 8 and revealed about 800 cc of the bloody fluid. Parvimonas micra was detected in a culture of the pericardial effusion and blood. Although intravenous antibiotic therapy was initiated for purulent pericarditis, his fever persisted. Computed tomography of the chest performed on Day 14 showed an abscess cavity in the pericardial space around the right atrium (RA). Furthermore, transoesophageal echocardiography revealed vegetation in the RA. Emergency surgery confirmed the presence of vegetation and minor perforation of the RA with communication to the abscess cavity. After surgical therapy, the patient clinically improved and was discharged on Day 51.
Discussion:
In cases of acute pericarditis, purulent pericarditis should be considered if clinical improvement is not observed after initial treatment with anti-inflammatory drugs. Once the diagnosis of purulent pericarditis is made, aggressive source control is necessary for improved clinical outcomes.
Insights
Purulent pericarditis caused by Parvimonas micra is rare but serious. Prompt diagnosis and aggressive treatment, including source control, are crucial for patient survival and improved outcomes in acute pericarditis.
Area of Science:
- Cardiology
- Infectious Diseases
- Critical Care Medicine
Background:
- Purulent pericarditis is a rare condition with high mortality without treatment.
- It can lead to severe complications like tissue and organ perforation.
- Parvimonas micra is an exceptionally rare cause of purulent pericarditis.
Purpose of the Study:
- To report a rare case of purulent pericarditis caused by Parvimonas micra.
- To highlight the importance of considering purulent pericarditis in refractory acute pericarditis.
- To emphasize the necessity of aggressive management for favorable outcomes.
Main Methods:
- A 70-year-old male presented with chest pain and symptoms of acute pericarditis.
- Diagnosis was confirmed by pericardiocentesis revealing Parvimonas micra in pericardial fluid and blood.
- Advanced imaging (CT, TEE) identified a pericardial abscess and right atrial vegetation/perforation.
Main Results:
- Initial anti-inflammatory treatment failed, necessitating pericardiocentesis.
- Parvimonas micra was identified as the causative agent.
- Surgical intervention was required for source control, leading to clinical improvement.
Conclusions:
- Purulent pericarditis must be suspected in acute pericarditis cases unresponsive to anti-inflammatory drugs.
- Early and aggressive source control is vital for managing purulent pericarditis.
- Successful treatment involved antibiotics, pericardiocentesis, and surgical intervention.
Related Concept Videos
Pericarditis I: Introduction
Endocarditis I: Introduction
Pericarditis II: Clinical Features and Diagnostic Tests
Pericarditis III: Medical Management
Endocarditis II: Clinical Features of Infective Endocarditis
Pericarditis IV: Nursing Management

