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[Arrhythmia profile and heart rate in hyperthyroidism].

S Bischoff1, G Kahaly, K von Olshausen

  • 1II. Medizinische Klinik und Poliklinik, Universität Mainz.

Deutsche Medizinische Wochenschrift (1946)
|April 15, 1988
PubMed
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Hyperthyroidism patients show a tendency for supraventricular arrhythmias, not ventricular ones. Antithyroid treatment reduced supraventricular tachycardias but did not alter heart rate day-night differences.

Area of Science:

  • Cardiology
  • Endocrinology
  • Clinical Medicine

Background:

  • Hyperthyroidism is associated with cardiovascular complications, including arrhythmias.
  • Understanding arrhythmia profiles in hyperthyroid patients is crucial for effective management.

Purpose of the Study:

  • To analyze arrhythmia profiles and heart rate patterns in hyperthyroid patients before, during, and after antithyroid treatment.
  • To compare these profiles with a control group without heart disease.

Main Methods:

  • 24-hour ECG monitoring was performed on 48 hyperthyroid patients and 50 controls.
  • Thyroid hormone (T3) levels and heart rates were recorded at different treatment stages.
  • Arrhythmia classification (Lown criteria) and heart rate variability were assessed.

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Main Results:

  • Hyperthyroid patients showed a normal ventricular arrhythmia profile but a high incidence of supraventricular extrasystoles, particularly in older individuals.
  • A significant correlation existed between T3 levels and nocturnal heart rate (r=0.74, P<0.001).
  • Antithyroid treatment reduced supraventricular tachycardias but did not alter the day-night heart rate difference.

Conclusions:

  • Hyperthyroidism is linked to a predisposition for supraventricular arrhythmias, influenced partly by age.
  • Antithyroid therapy effectively manages supraventricular tachycardias but does not normalize heart rate diurnal variations.