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Vaccination in preterm and low birth weight infants in India

Santosh Soans1, Attila Mihalyi2, Valerie Berlaimont3

  • 1Paediatrics, AJ Institute of Medical Sciences, Mangalore, India.

Human Vaccines & Immunotherapeutics
|February 18, 2021
PubMed

Insights

Vaccination delays in preterm and low birth weight (LBW) infants in India increase their risk of death from vaccine-preventable diseases (VPDs). Increased awareness and addressing barriers are crucial for timely immunization.

Area of Science:

  • Pediatrics
  • Immunology
  • Public Health

Background:

  • India faces high neonatal and infant mortality, partly due to rising preterm and low birth weight (LBW) births.
  • Immune system immaturity in these infants heightens their vulnerability to vaccine-preventable diseases (VPDs).

Purpose of the Study:

  • To review the scientific literature on VPD risks, vaccination delays, and associated factors in Indian preterm and LBW infants.

Main Methods:

  • A narrative review of the scientific literature was conducted.
  • Data on VPD risks and vaccination patterns in Indian preterm and LBW infants were screened.

Main Results:

  • Vaccination is frequently delayed in preterm and LBW infants despite recommendations.
  • Barriers include post-birth complications, lack of awareness, and safety concerns.
  • Delayed vaccination increases infection risk, complications, and mortality.

Conclusions:

  • Addressing barriers and increasing awareness are essential to improve vaccination rates in vulnerable Indian infants.
  • Timely vaccination is critical to reduce mortality from VPDs in preterm and LBW infants.

Keywords:
IndiaNeonatalimmunizationinfectious diseaselow birth weightprematuritypretermvaccination

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