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Selective effects of PHA on rat brush border hydrolases along the crypt-villus axis
J M Rouanet1, J Lafont, J L Zambonino-Infante
1Laboratoire de Physiologie de la Nutrition, Centre de Génie et Technologie Alimentaires, Montpellier, France.
Abstract:
The mechanism of the toxicity of lectin from Phaseolus vulgaris seeds has been investigated on rat enterocytes. Cell isolation procedures showed a selectivity in the loss of brush border hydrolases; this indicated that the microvilli blebbing was not the only mechanism of action of lectins on rat enterocytes.