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[Action of anti-arrhythmia agents in ischemia and hyperoxia]

S I Kedrov, K M Reznikov, A N Leonov

Farmakologiia I Toksikologiia

|January 1, 1988

Abstract:

During experiments (128 rabbits) it was shown that under ischemia and hyperoxia the pharmacodynamics of lidocaine, anaprilin and ethacizine changed in centrogenic and peripheral arrhythmias induced by aconitine. Hyperoxia significantly potentiated the antiarrhythmic effect of the drugs except lidocaine action in centrogenic arrhythmias.

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