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Fetal Circulation01:14

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Fetal circulation is a unique system that facilitates the exchange of gases, nutrients, and waste products between the developing fetus and the mother. This intricate process takes place through a special organ called the placenta.
Two umbilical arteries transport blood from the fetus to the placenta. At the placenta, the blood absorbs oxygen and nutrients while simultaneously eliminating waste products. This oxygen-enriched and nutrient-rich blood then returns to the fetus through one...
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Related Experiment Video

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Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
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What we know about placenta accreta spectrum (PAS).

Xiyao Liu1, Yu Wang2, Yue Wu1

  • 1Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China; China-Canada-New Zealand Joint Laboratory of Maternal and Fetal Medicine, Chongqing Medical University, No.1 Yixueyuan Road, Yuzhong District, Chongqing 400016, China.

European Journal of Obstetrics, Gynecology, and Reproductive Biology
|February 18, 2021
PubMed
Summary
This summary is machine-generated.

Placenta accreta spectrum (PAS) is a pregnancy complication involving abnormal placental implantation. This review covers PAS prevalence, risk factors, and management, offering a new visualized workflow for patient care.

Keywords:
Clinical managementPlacenta accreta spectrumReview

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Area of Science:

  • Obstetrics and Gynecology
  • Maternal-Fetal Medicine
  • Reproductive Health

Background:

  • Placenta accreta spectrum (PAS) encompasses conditions of abnormal placental implantation.
  • The incidence of PAS has risen significantly in recent decades.
  • PAS poses severe clinical complications, necessitating comprehensive understanding and management.

Purpose of the Study:

  • To review and synthesize current evidence-based data on Placenta Accreta Spectrum.
  • To explore prevalence, risk factors, pathogenesis, and clinical aspects of PAS.
  • To propose future research directions and a management workflow for PAS.

Main Methods:

  • Comprehensive literature review of evidence-based data on PAS.
  • Synthesis of information regarding prevalence, risk factors, pathogenesis, and clinical presentation.
  • Development of a visualized management workflow for PAS.

Main Results:

  • The review summarizes key findings on PAS prevalence, risk factors, and pathogenesis.
  • Clinical presentation, prenatal screening, and management strategies are detailed.
  • A novel three-step visualized workflow (predelivery, during delivery, postdelivery) for PAS management is presented.

Conclusions:

  • PAS is an increasingly prevalent and serious obstetric complication.
  • Effective management requires a thorough understanding of its multifaceted aspects.
  • The proposed visualized workflow offers a structured approach to PAS patient care.