Related Experiment Video
Updated: Nov 17, 2025
Mouse Model of Surgical Uterine Injury and Subsequent Pregnancy Outcomes
Published on: June 27, 2025
What we know about placenta accreta spectrum (PAS)
1Department of Obstetrics, The First Affiliated Hospital of Chongqing Medical University, No. 1 Youyi Road, Yuzhong District, Chongqing 400016, China; China-Canada-New Zealand Joint Laboratory of Maternal and Fetal Medicine, Chongqing Medical University, No.1 Yixueyuan Road, Yuzhong District, Chongqing 400016, China.
Insights
Placenta accreta spectrum (PAS) is a pregnancy complication involving abnormal placental implantation. This review covers PAS prevalence, risk factors, and management, offering a new visualized workflow for patient care.
Area of Science:
- Obstetrics and Gynecology
- Maternal-Fetal Medicine
- Reproductive Health
Background:
- Placenta accreta spectrum (PAS) encompasses conditions of abnormal placental implantation.
- The incidence of PAS has risen significantly in recent decades.
- PAS poses severe clinical complications, necessitating comprehensive understanding and management.
Purpose of the Study:
- To review and synthesize current evidence-based data on Placenta Accreta Spectrum.
- To explore prevalence, risk factors, pathogenesis, and clinical aspects of PAS.
- To propose future research directions and a management workflow for PAS.
Main Methods:
- Comprehensive literature review of evidence-based data on PAS.
- Synthesis of information regarding prevalence, risk factors, pathogenesis, and clinical presentation.
- Development of a visualized management workflow for PAS.
Main Results:
- The review summarizes key findings on PAS prevalence, risk factors, and pathogenesis.
- Clinical presentation, prenatal screening, and management strategies are detailed.
- A novel three-step visualized workflow (predelivery, during delivery, postdelivery) for PAS management is presented.
Conclusions:
- PAS is an increasingly prevalent and serious obstetric complication.
- Effective management requires a thorough understanding of its multifaceted aspects.
- The proposed visualized workflow offers a structured approach to PAS patient care.
Abstract:
Placenta accreta spectrum (PAS) is an umbrella term for a variety of pregnancy complications due to abnormal placental implantation, including placenta accreta, placenta increta and placenta percreta. During the past several decades, the prevalence of PAS has been increasing, and the clinical importance of this disease is significant because of the severe complications. In this review, we summarized the available evidence-based data for PAS in various aspects: prevalence, risk factors, pathogenesis, clinical presentation and prenatal screening, and clinical management. Meanwhile, we provided a series of prospects in each section for further studies on PAS. Moreover, we first present a visualized workflow for the management of PAS from three steps: predelivery, during delivery and postdelivery.
More Related Videos
09:52Accurate and Simple Evaluation of Vascular Anastomoses in Monochorionic Placenta using Colored Dye
Published on: September 5, 2011
09:51Model Surgical Training: Skills Acquisition in Fetoscopic Laser Photocoagulation of Monochorionic Diamniotic Twin Placenta Using Realistic Simulators
Published on: March 21, 2018
