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Relationship between renal volume and atherosclerosis in nondiabetic hypertensive patients with normal glomerular

Emrah Selvi1, Aysun Aybal Kutlugun2, Nuray Gulden Tangal3

  • 1Department of Internal Medicine, Health Science University, Keçioren Training and Research Hospital, Ankara, Turkey.

Clinical and Experimental Hypertension (New York, N.Y. : 1993)
|February 19, 2021
PubMed

Insights

Renal volume, measured by ultrasound, can predict atherosclerosis in hypertensive patients. This easy method aids in early detection of cardiovascular risk factors.

Area of Science:

  • Nephrology
  • Cardiology
  • Radiology

Background:

  • Cystatin C (CysC) and cardiovascular risk are linked in hypertensive patients.
  • Limited research exists on renal volume's association with atherosclerosis.
  • This study explores CysC, renal volume, and atherosclerosis in hypertension.

Purpose of the Study:

  • To investigate the association between renal volume, cystatin C (CysC), and atherosclerosis in hypertensive patients.
  • To determine if renal volume predicts subclinical atherosclerosis (measured by CIMT).
  • To assess the utility of ultrasonographic renal volume measurement in hypertensive individuals.

Main Methods:

  • 133 hypertensive patients and 80 controls were assessed.
  • Blood samples for CysC, carotid intima-media thickness (CIMT), and renal volume via ultrasound were measured.
  • Statistical analysis compared laboratory findings, CysC, CIMT, and renal volume between groups.

Main Results:

  • No significant difference in renal volume between hypertensive and control groups.
  • CIMT was significantly higher in hypertensive patients (p=.003).
  • Renal volume correlated significantly with CIMT (r=0.213, p=.001) and independently predicted it.

Conclusions:

  • Ultrasonographic renal volume measurement is a simple, quick method.
  • Renal volume can be a useful predictor of atherosclerosis in hypertensive patients with GFR >60 ml/min.
  • This imaging technique may aid in early cardiovascular risk assessment.

Keywords:
Cystatin Catherosclerosishypertensionrenal volume

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