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The Impact of Uncontrolled Hypertension on the Longitudinal Systolic Function of the Left Ventricle

Nabila Soufi Taleb Bendiab1, Salim Benkhedda2, Latifa Henaoui3

  • 1Department of Cardiology, Faculty of Medicine, Aboubekr Belkaid University Hospital Tlemcen, Tlemcen, Algeria.

Current Hypertension Reviews
|February 19, 2021
PubMed

Insights

Uncontrolled hypertension impairs left ventricular (LV) longitudinal systolic function, even when ejection fraction appears normal. Deformation imaging reveals reduced longitudinal strain and strain rate in hypertensive patients.

Area of Science:

  • Cardiology
  • Echocardiography
  • Hypertension Research

Background:

  • Left ventricular (LV) longitudinal function assessment is crucial for detecting LV contractile impairment.
  • Uncontrolled hypertension poses a significant risk to cardiovascular health.
  • Early detection of systolic dysfunction is vital for timely intervention.

Purpose of the Study:

  • To investigate the impact of uncontrolled hypertension on LV longitudinal systolic performance.
  • To identify subtle changes in systolic function not detectable by conventional echocardiography.
  • To correlate hypertension control status with LV systolic function parameters.

Main Methods:

  • Echocardiographic evaluation of 400 hypertensive patients (271 uncontrolled, 112 controlled).
  • Calculation of LV mass and assessment of diastolic function.
  • Utilized 2D speckle tracking for evaluating LV longitudinal strain and strain rate.

Main Results:

  • Uncontrolled hypertensive patients showed increased LV mass and impaired diastolic function.
  • Conventional echocardiography did not reveal significant systolic function impairment.
  • Deformation imaging demonstrated reduced longitudinal strain and strain rate in uncontrolled hypertensive patients.

Conclusions:

  • LV longitudinal strain and strain rate are reduced in patients with uncontrolled hypertension.
  • 2D speckle tracking is more sensitive than conventional echocardiography for detecting early systolic dysfunction in hypertension.
  • Hypertension control status significantly impacts LV longitudinal systolic performance.
Abstract

Keywords:
LV massUncontrolled hypertensionechocardiographystrainsystolicventricle

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