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Natural selection influences the frequencies of particular alleles and phenotypes within populations in several different ways. Primarily, natural selection can be directional, stabilizing, or disruptive. Directional selection favors one extreme trait and shifts the population towards that phenotype while selecting against individuals displaying alternate traits. Stabilizing selection favors an intermediate trait with a narrow range of variation. Deviation from the optimal phenotype towards an...
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Editor-in-Chief's Top Picks From 2020.

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    This summary is machine-generated.

    This annual review highlights 100 top cardiovascular research papers from JACC, covering diverse specialties and including highly accessed articles. It offers a concise overview of significant advancements in cardiology.

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    Area of Science:

    • Cardiology
    • Cardiovascular Research
    • Medical Publishing

    Background:

    • The Journal of the American College of Cardiology (JACC) publishes significant research across various cardiovascular specialties.
    • Identifying and disseminating the most impactful research is crucial for advancing clinical practice and patient outcomes.

    Discussion:

    • This compilation represents a curated selection of the year's most influential cardiovascular research.
    • It includes original investigations, review articles, and highly accessed papers, reflecting both expert opinion and reader engagement.
    • The selection process ensures a broad representation of key areas within cardiovascular medicine.

    Key Insights:

    • Presents the top 100 JACC papers of the year, categorized by specialty for easy navigation.
    • Features abstracts and central illustrations for enhanced understanding and retention.
    • Incorporates papers based on editorial selection, high access rates, and JACC Editorial Board recommendations.

    Outlook:

    • Provides a valuable resource for clinicians, researchers, and trainees to stay abreast of critical cardiovascular findings.
    • Facilitates a comprehensive understanding of the year's advancements in areas such as cardiac failure, hypertension, and valvular heart disease.
    • Serves as a benchmark for important research trends and future directions in cardiovascular medicine.