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Fentanyl transdermal patches induced chemical leucoderma
Sanhapan Wattanapisit1, Apichai Wattanapisit2,3, Pornnapat Laksanapiya1
1Palliative Care Unit, Thasala Hospital, Nakhon Si Thammarat, Thailand.
BMJ Supportive & Palliative Care
|February 19, 2021
Summary
Chemical leucoderma, a rare condition from chemical exposure, can be induced by fentanyl transdermal patches. This case highlights depigmented lesions appearing after prolonged patch use.
Area of Science:
- Dermatology
- Toxicology
Background:
- Chemical leucoderma presents as hypopigmentation due to chemical exposure.
- Fentanyl transdermal patches are an uncommon cause of this condition.
Observation:
- A 53-year-old man developed depigmented lesions on areas of fentanyl transdermal patch application.
- The patient had used patches for approximately two years to manage chronic back pain.
Findings:
- The clinical presentation strongly suggested chemical leucoderma induced by fentanyl.
- The relationship between fentanyl dosage, exposure duration, and leucoderma development requires further investigation.
Implications:
- Discontinuation of fentanyl patches may lead to spontaneous repigmentation.
- Treatment options for chemical leucoderma include phototherapy and various topical agents.
- Monitoring for spontaneous repigmentation post-cessation is recommended.
Keywords:
pain
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